HSIEH, PEI SHAN,谢佩珊,謝佩珊,TSAI, YI CHUN,蔡宜钧,蔡宜鈞,KUO, ALBERT,郭仲伟,郭仲偉,CHEN, YI CHUN,陈怡君,陳怡君
申请号：
TW099113843
公开号：
TWI542353B
申请日:
2010.04.30
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
An anti-vaginitis food composition and/or pharmaceutical composition includes, Lactobacillus acidophilus F-1 (FIRDI stock No. BCRC 910469), Lactobacillus rhamnosus CT-53 (FIRDI stock No. BCRC 910468) or combinations thereof, wherein the Lactobacillus strains are resistant to acid, bile and Clotrimazole. The present invention may inhibit TNF- α secretion and promote IL-10 secretion of dendritic cells and therefore inhibit inflammation and inflammation in vagina mucosa cell. The present invention may be presented as oral and direct contact with vagina probiotics.一種用以抗陰道炎的食品組合物及/或醫藥組合物，包含：至少一乳酸菌菌株，其具有胃酸、膽鹽及抑霉劑克黴唑(Clotrimazole)耐受性並選自以下任一或多種組合之菌株：嗜酸乳酸桿菌(Lactobacillus acidophilus)F-1菌株，寄存編號BCRC 910469、鼠李糖乳酸桿菌(Lactobacillus rhamnosus)CT-53菌株，寄存編號BCRC 910468或其組合。本發明可抑制樹狀細胞之腫瘤壞死因子-α(TNF-α)之產生及/或促進細胞介白素-10(IL-10)之產生，並進而抑制發炎反應及陰道黏膜細胞發炎之症狀。本發明可以口服益生菌及直接接觸於患處之益生菌製劑形式之方式存在。
