ITOH, TETSUJI,JEON, INGYU,MANGION, IAN,QIAN, GANG,SHERRY, BENJAMIN D.,GAUTHIER, DONALD R.,CAO, YANG
申请号:
CA2892919
公开号:
CA2892919A1
申请日:
2013.12.04
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention is directed to a novel process for synthesizing 3-(substituted phenoxy)-1-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl])-pyridin-2(1H)-one derivatives. The compounds synthesized by the processes of the invention are HIV reverse transcriptase inhibitors useful for inhibiting reverse transcriptase, HIV replication and the treatment of human immunodeficiency virus infection in humans.