Disclose for eyes cure the disease or the method for situation, special retinopathy, ocular edema and ocular angiogenesis. The non-limiting examples of these diseases or situation include diabetic macular edema, senile macular degeneration (wet or dry form), choroidal neovascularization, diabetic retinopathy, retinal vein occlusion (center or branch), eye traumas, surgical operation causes oedema, and surgical operation causes neovascularization, cystoid macular edema, eye ischemic, uveitis etc.. No matter these diseases or situation are characterized in that being incremented by eye vascular system or on-progressive, and though an acute disease or situation as a result, or a chronic disease or situation.