TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
KHALILI, KAMEL,MALCOLM, THOMAS
申请号：
CA3001130
公开号：
CA3001130A1
申请日:
2016.10.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Compositions include endonucleases of the family Cpf1 (CRISPR from Prevotella and Francisella 1) and at least one guide RNA (gRNA) complementary to a target sequence in a gene to specifically guide the Cpf1 endonuclease to the target site in a host cell in vitro or in vivo. Methods of treating a subject include the use of one or more of these compositions.
