A method and system for determining Apnea-Hypopnea Index (AHI) values are disclosed. The method comprises determining at least one sensor stream using at least one detected physiological signal, and processing the at least one sensor stream to automatically determine the AHI values. The system includes a sensor to detect at least one physiological signal, a processor coupled to the sensor, and a memory device coupled to the processor, wherein the memory device includes an application that, when executed by the processor, causes the processor to determine at least one sensor stream using at least one detected physiological signal and to process the at least one sensor stream to automatically determine the AHI values.