非抗原性分枝ポリマーコンジュゲート

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专利权人:

エンゾン,インコーポレーテッド

发明人:

グリーンワルド,リチャード,ビー.,マルチネス,アンソニー,ジェイ.

申请号：

JP2010024340

公开号：

JP4961025B2

申请日:

2010.02.05

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.

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