Hartmuth C. Kolb,Joseph C. Walsh,Dhanalakshmi Kasi,Vani P. Mocharla,Bing Wang,Umesh B. Gangadharmath,Brian A. Duclos,Kai Chen,Wei Zhang,Gang Chen,Henry Clifton Padgett,Farhad Karimi,Peter J. H. Scott
申请号:
US12862955
公开号:
US08354092B2
申请日:
2010.08.25
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present application discloses methods for identifying inhibitors with high binding-affinity for the carbonic anhydrase-IX (CA-IX) enzyme using click chemistry and uses the candidates thereof as positron emission tomography (PET) imaging agents.