A method of guiding a cardiac treatment using a functional imaging modality, comprising: providing functional imaging modality data from a functional imaging modality which images an intrabody volume of a patient containing a heart, the patient having been injected with an imaging agent having a nervous tissue uptake by an autonomic nervous system (ANS) of the heart, the ANS comprising at least one GP locating the at least one GP innervating the heart based on the functional imaging modality data and providing the located at least one GP.