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含氮雜環化合物的鹽或其結晶、藥品組合物及FLT3抑制劑
专利权人:
FUJIFILM CORPORATION
发明人:
MIZUMOTO Shinsuke,MATSUMOTO Takuya,水本真介,松本拓也
申请号:
HK16107873.9
公开号:
HK1219946A
申请日:
2016.07.06
申请国别(地区):
HK
年份:
2017
代理人:
摘要:
An object of the present invention is to provide a compound and pharmaceutical composition showing superior stability and/or solubility, etc. and having superior FLT3 inhibitory activity. The present invention provides a salt of (S,E)-N-(1-((5-(2-((4-cyanophenyl)ammo)-4-(propylanmio)pyrimidin-5-yl)pent-4-yn-1-yl)amino)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methylbut-2-enamide, or a crystal thereof. Since the salt or a crystal thereof has superior FLT3 inhibitory activity and shows superior physicochemical properties as drugs, such as storage stability, solubility, and so forth, it is useful for treatments of diseases or conditions relating to FLT3. The present invention also provides a pharmaceutical composition and FLT3 inhibitor containing the salt or a crystal thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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