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METHOD FOR IMPROVING CELL PERMEABILITY TO FOREIGN PARTICLES
专利权人:
发明人:
SHAH JYOTSANA S.,SHAH JYOTSANA S.,WELTMAN HELENA,WELTMAN HELENA
申请号:
PL06788834
公开号:
PL1924252T3
申请日:
2006.07.27
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The present invention provides a method for allowing foreign particles to penetrate, very efficiently, the cell wall, cell membrane, organelle membrane and/or nuclear membrane of a cell and hybridizing or binding to the complimentary target in the cell. The cells may be from a culture or from specimens obtained from a patient. The foreign particle can be a probe consisting of, for example, either individually or in any combination of two or more of the following: DNA, RNA, peptide nucleic acids (PNA), glycopeptides, lipopeptides, glycolipids or prions. The target is a cell, a cell component or, preferably, a pathogen or pathogen component. The pathogen can be, for example, bacteria, fungi, yeast or viruses.
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