KOHNERT, ULRICH,POHLING, SYLKE,HELLERBRAND, KLAUS,HAPPERSBERGER, PETER
申请号:
CA2466947
公开号:
CA2466947C
申请日:
2002.03.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to a device having osteoinductive andosteoconductive properties in vivo comprising a carrier containing calciumphosphate and an osteoinductive protein, wherein said carrier is homogenouslycoated with said protein. Moreover, the present invention relates to a methodfor the production of a device having osteoinductive and osteoconductiveproperties in vivo. The invention encompasses a pharmaceutical compositioncomprising the device of the invention or a device which is obtainable by themethod of the invention and relates to the use of said device for thepreparation of a pharmaceutical composition to be used for bone augmentation,for treating bone defects, for treating degenerative and traumatic discdisease, for treating bone dehiscence or to be used for sinus floor elevation.Finally, the invention relates to a kit comprising the device of the inventionor a device which is obtainable by the method of the invention.