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Crystalline forms of the 4-pyrimidinesulfamide derivative aprocitentan
专利权人:
Idorsia Pharmaceuticals Ltd
发明人:
Bolli, Martin,Kohler, Philipp,Schindelholz, Ivan,Von Raumer, Markus
申请号:
AU2018225309
公开号:
AU2018225309A1
申请日:
2018.02.26
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention concerns novel crystalline forms of {5-(4-bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-sulfamide, processes for the preparation thereof, pharmaceutical compositions comprising said crystalline forms, pharmaceutical compositions prepared from such crystalline forms, and their use as endothelin receptor antagonists. It also relates to new uses of {5-(4-bromo-phenyl)-6-[2-(5-bromo-pyrimidin-2-yloxy)-ethoxy]-pyrimidin-4-yl}-sulfamide, either alone or in combination with other active ingredients or therapeutic agents.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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