One or more low calorie sugar substitute compositions have been provided for different end applications. The one or more low calorie sugar substitute compositions comprise a carrier in the range of 80% to 98% by weight in the composition one or more high intensity sweeteners in the range of 0.1% to 13% by weight in the composition a sweetness enhancer in the range of 0.01 % to 1 % by weight in the composition one or more bulking agents in the range of 0.1 % to 5% by weight in the composition a masking agent in the range of 0.5%> to 1.0% by weight in the composition and one or more additives in an amount of not more than 7% by weight in the composition. The low calorie sugar substitute composition exhibits a calorific value in the range of 22 to 115 Kcal (per equivalent quantity of the composition with same sweeteners factor as that of 100 grams of sugar) and a glycemic index in the range of 15 to 22. The low calorie sugar substitute composition operates at a temperature range of-50°C to +350°C. The present invention also provides a process for preparing a low calorie sugar substitute composition.