PROBLEM TO BE SOLVED: To provide a GIP secretion inhibitor useful as a pharmaceutical or food, capable of promoting digestion and/or ameliorating a dull feeling in the stomach through inhibiting the secretion of a digestive tract hormone (GIP) having gastric acid secretion inhibitory activity and/or gastric motility inhibitory whose secretion is activated with lipids and the like in diet, in taking a meal.SOLUTION: The postprandial GIP secretion inhibitor comprises, as an active ingredient for promoting digestion and/or ameliorating a dull feeling in the stomach, potassium alginate which significantly inhibits postprandial GIP secretion after taking a meal compared to sodium alginate. When the secretion inhibitor is to be used in the form of an oral liquid preparation, potassium alginate with a weight-average molecular weight of 10,000-50,000 is used.COPYRIGHT: (C)2009,JPO&INPIT【課題】摂食時、食餌中の脂質等によりその分泌が亢進される胃酸分泌抑制作用や胃運動抑制作用を有する消化管ホルモン(GIP)の分泌を阻害することで、消化促進や胃もたれの改善をもたらす、医薬又は食品として有用なGIP分泌抑制剤の提供。【解決手段】アルギン酸ナトリウムと比較しても、食後のGIP分泌を著しく抑制するアルギン酸のカリウム塩を、消化促進や胃もたれ改善の有効成分とし、更に経口用液体製剤の形態で用いる場合には重量平均分子量が10,000~50,000のアルギン酸カリウムを用いる食後GIP分泌抑制剤。【選択図】なし
