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COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS
专利权人:
THE SCRIPPS RESEARCH INSTITUTE
发明人:
WAN, YONGQIN,WANG, XING,BOITANO, ANTHONY,COOKE, MICHAEL,PAN, SHIFENG,SCHULTZ, PETER G
申请号:
NZ59243509
公开号:
NZ592435A
申请日:
2009.10.29
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
Disclosed is a compound of Formula I e.g. 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl- 9H-purin-6-ylamino)ethyl)phenol in which the variables are defined in the specification for treating acute myeloid leukemia, acute lymphoblastic leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, a myeloproliferative disorder, a myelodysplastic syndrome, multiple myeloma, Non-Hodgkins lymphoma, Hodgkins disease, aplastic anemia, pure red cell aplasia, paroxysmal nocturnal hemoglobinutia, Fanconi anemia, thalassemia major, sickle cell anemia, severe combined immunodeficiency, Wiskott-Aldtich syndrome, hemophagocytic lymphohistiocytosis and an inborn error of metabolism.
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