PROBLEM TO BE SOLVED: To provide a novel compound which has an Akt inhibitory effect and a cell growth inhibitory effect and a medicine useful in prevention and/or remedy of Akt-related diseases, especially cancer, based on the Akt inhibitory effect.SOLUTION: Piperazine derivatives of formula (I) having a hydroxyl group or their salts are provided. In formula (I), R1 to R7 are as defined in the specification.COPYRIGHT: (C)2015,JPO&INPIT【課題】Akt阻害作用を有し、かつ細胞増殖抑制効果を有する新規な化合物を提供すること。またAkt阻害作用に基づき、該Aktが関与する疾患、特に癌の予防及び/又は治療に有用な医薬を提供すること。【解決手段】式(I)[式中、R1~R7は明細書中で定義したとおりの意味を有する]で表される、ヒドロキシル基を有するピペラジン誘導体又はその塩。【選択図】なし
