Mehdi PABORJI,Robert V. TUOHY, III,Peter R.P. FREED,Roger S. FLUGEL
申请号:
US15949911
公开号:
US20180243218A1
申请日:
2018.04.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed herein are pharmaceutical compositions comprising a plurality of first beads each comprising: a core; a first layer comprising pilocarpine or a pharmaceutically acceptable salt thereof; and a second layer comprising a first polymer. Also disclosed are pharmaceutical compositions comprising a plurality of second beads each comprising: a core; and a first layer comprising tolterodine or a pharmaceutically acceptable salt thereof. Further disclosed are pharmaceutical formulations comprising: a) a plurality of the first beads; b) a plurality of the second beads; or c) a plurality of the first beads and a plurality of the second beads.