A method improving air quality and reducing healthcare-associated infections performed by a cleaning personnel includes the steps of equipping a cleaning cart with a plurality of single-use microfiber cloths and a plurality of microfiber mops, wherein the cleaning cart includes a vacuum cleaning apparatus with an extensible vacuum hose and a plurality of attachments, positioning the cleaning cart outside of an occupied patient room, vacuuming the patient room with the vacuum hose including first and second attachments, disinfecting the surfaces that a patient may contact with a first microfiber cloth soaked in a disinfectant solution, cleaning at least one bathroom fixture with a second microfiber cloth soaked in the disinfectant solution, mopping the floor area including the floor area of the patient restroom with a microfiber mop charged with a neutral cleaner, and placing the microfiber mop in a plastic bag.