Complex drug acceptable formulations, including abiraterona acetate complex and acceptable pre drug formulations, preparation processes, and drug compounds containing these compounds. The compound formula has high physical and chemical properties and has little effect on food, Requirement 1: a stable compound characterized by physical and chemical properties and high biological properties, including (a) abiratner acetate as an active compound,Or a mixture of active compounds containing ammonium nitrite acetic acid； (b) at least one compound molding agent selected from the glycerin of polyethylene glycol, which is composed of mono glycerin, diglic or triglyceride, polyethylene glycol, hydroxypropyl cellulose, and polox, Vinyl glycol / vinyl acetate, polyethylene glycol, strip (2-ethyl-2-oxazolina),Polyvinyl chloride (PVC) and epoxy propylene block copolymers, and polyvinyl chloride (maleic acid / methyl vinyl ether),The graft copolymers were based on poly (vinyl chloride) - vinyl acetate - polyethylene - ethyl ester, polyoxy 15, epoxy / propylene block copolymers, polyethylene and polyethylene - butanediol graft copolymers, and D - A - vinyl chloride - polyethylene - 1000； (c) Ideally, a precursor chemical acceptable for a variety of drugs； containing particles smaller than 600 nm and having one or more of the following properties: it can be redesigned immediately in a physically relevant medium；it has a higher dissolution rate； it is stable in a solid form or in a solution or colloidal dispersion； it has an apparent solubility in water of at least 0.6 mg / ml； on X-ray analysis, it presents a solid shape with an amorphous character； have a PAMPA permeability of at least 0.5 × 10⁻⁶ cm / s when dispersed in distilled water, which does not decrease over time over a period of at least 3 months； does not have a positive effect with food (it is characterized by a ratio between the fed state and the fast that is less than 1.25),As a result, the dose can be significantly re
