Ronald M. Evans,Liming Pei,Michael Downes,Ruth T. Yu,Annette Atkins
申请号：
US15709292
公开号：
US20180015057A1
申请日:
2017.09.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein are methods and kits for increasing cardiac contraction, increasing mitochondrial activity, and/or increasing oxphos activity. Such methods include use of therapeutically effective amounts of one or more agents that increases estrogen-related receptor (ERR) α activity and one or more agents that increases ERRγ activity. In some examples, the method further includes administering a therapeutically effective amount of one or more agents that increases mitofusin 1 (Mfn1) activity.
