Rush University Medical Center;Massachusetts General Hospital
发明人:
Jochen Reiser,Eunsil Hahm,Sanja Sever
申请号:
US15560926
公开号:
US20180252705A1
申请日:
2016.03.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treating kidney diseases or disorders and methods of identifying agents for treatment of kidney diseases or disorders are provided. The method includes administering to a subject in need thereof, an effective amount of an agent which inhibits myeloid progenitor cells in the subject from producing soluble urokinase receptor (suPAR). The method includes administering the agent to a patient, where the patient, has an increased number of Gr-1 low cells relative to a control.