ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.;COA THERAPEUTICS, INC.
发明人:
LEE, RICHARD E.,TANGALLAPALLY, RAJENDRA P.,ROCK, CHARLES O.,JACKOWSKI, SUZANNE,EDWARDS, ANNE V.,YUN, MI, KYUNG,SUBRAMANIAN, CHITRA,ZAMBONI, ROBERT,REDDY, T. JAGADEESWAR
申请号:
CA3086671
公开号:
CA3086671A1
申请日:
2018.12.26
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.