The present disclosure relates to a pick-up and delivery system including a pick-up assembly and a delivery assembly. The pick-up assembly includes a robotic arm, a pick-up device rotatably mounted on the robotic arm, and a first vacuum pressure supply port operably connected to the pick-up device. The delivery assembly includes an insertion device. The insertion device may include an insertion member having a tip and a release assistance piston arranged inside the insertion member. The release piston is moveable between an extended position and a retracted position. When the release assistance piston is in the extended position, a proximal end of is substantially flush with an end of the insertion member. Further aspects are directed towards methods for grasping and releasing an object with a pick-up and delivery system.