Provided are: an autonomic nerve regulator and a food composition for autonomic nerve regulation exhibiting the effect of regulating autonomic nerves, in particular the effect of regulating autonomic nerve function in response to environmental changes in the psychological stress environment； the use of eleutheroside E to produce an autonomic nerve regulator； and an autonomic nerve regulation method. An autonomic nerve regulator having as an active ingredient eleutheroside E, which regulates autonomic nerve function in response to environmental changes in the psychological stress environment； and a food composition for autonomic nerve regulation containing as an active ingredient eleutheroside E. Acceleration of sympathetic nerve function is suppressed and the decline in parasympathetic nerve function is suppressed in environmental changes in the psychological stress environment.本發明之課題為提供發揮調節自律神經之效果，特別是對應朝向心理壓力環境之環境變化而調節自律神經機能之效果的自律神經調節劑及自律神經調節用食品組成物。 本發明之解決手段為對應朝向心理壓力環境之環境變化而調節自律神經機能的以刺五加苷E(eleutheroside E)作為有效成分之自律神經調節劑及含有刺五加苷E作為有效成分之自律神經調節用食品組成物。在朝向心理壓力環境之環境變化中，抑制交感神經機能的亢進，同時抑制副交感神經機能的低下。
