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AMINAL SALT AND CRYSTALL THEREOF
专利权人:
ONO PHARMACEUTICAL CO.; LTD.
发明人:
TANI, Kousuke,KINOSHITA, Akihiro,HANADA, Keisuke,ARATANI, Yoshiyuki,NEKADO, Takahiro,SHIMABUKURO, Atsushi
申请号:
DK13832178
公开号:
DK2891651T3
申请日:
2013.08.30
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
A compound that can be a therapeutic agent for underactive bladder which has low risk of side effects and can be administered orally is provided. Furthermore, a crystal which is advantageous in view of the stability, long-term storage, handleability, easiness of the drug preparation or the like as a drug substance of medicaments is provided. Since a salt of 2-[(2-{(1R,5R)-2-oxo-5-[(1E,4S)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadien-1-yl]cyclopentyl}ethyl)thio]-1,3-thiazole-4-carboxylic acid or a diastereomeric mixture thereof and 4-piperidinemethanol is a chemically very stable crystal, it can be stored for a long time, and is very useful as a drug substance of medicaments.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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