The present invention relates to wetness indicator compositions that comprise at least one leuco dye and one color developer in a hot-melt adhesive matrix. Upon contact with water or with water-containing fluids, said wetness indicator compositions are apt to change their color from a colorless state to a colorful state or from a first colored state to a second colored state having a color different from the first one in particular, from a first colorless, white, or translucent state to a second state having a visible color, or vice versa. The disclosed wetness indicator compositions can be used as wetness/fluid indicators in various applications, e.g. in packaging articles and in absorbent articles in an absorbent mat or sheet or operatory cloth for medical use in a wound dressing product in an absorbent mat or sheet for food products.