A fluid filtration apparatus is provided which includes at least a functionalbiomedical device having an inlet and an outlet, a first biological fluid containerin fluid communication with the inlet of said functional biomedical device,a first biological fluid receiving container downstream of the functional biomedicaldevice in fluid communication with the outlet of the functional biomedical device,and having an excess of fluid, such as air or gas, in the first biological fluidcontainer or biological fluid receiving container (either placed therein duringmanufacture, or added later) sufficient to drain the system. A method of usingthe apparatus is disclosed.
