경희대학교 산학협력단;UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人:
KIM, Dong Hyun,김동현,HAN, Myung Joo,한명주
申请号：
KRKR2016/009961
公开号：
WO2017/047962A1
申请日:
2016.09.06
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention provides a novel lactobacillus and a use for same, the lactobacillus being separated from kimchi and thus highly safe, and having various types of biological activity such as memory improving activity, tight junction protein expression inducing activity, antioxidation activity, lipopolysaccharide (LPS) generation-suppressing activity, and β-glucuronidase inhibiting activity. The novel lactobacillus according to the present invention can be used as a functional food medicine material for preventing, improving, or treating degenerative brain diseases or cognitive function disorders.La présente invention concerne un nouveau lactobacillus et une utilisation de celui-ci, le lactobacillus étant isolé à partir de kimchi et, par conséquent, très sûr, et présentant divers types d'activité biologique, telle qu'une activité d'amélioration de la mémoire, une activité d'induction de l'expression de la protéine de jonction serrée, une activité anti-oxydation, une activité de suppression de la génération de lipopolysaccharide (LPS), et une activité inhibitrice de la β-glucuronidase. Le nouveau lactobacillus selon la présente invention peut être utilisé comme alicament pour prévenir, atténuer ou traiter des maladies cérébrales dégénératives ou des troubles de la fonction cognitive.본 발명은 김치에서 분리되어 안전성이 높고 기억력 개선 활성, 밀착연접단백질(tight junction protein) 발현 유도 활성, 항산화 활성, 지질다당류(lipopolysaccharide, LPS) 생성 억제 활성 또는 베타-글루쿠로니다제(β-glucuronidase) 저해 활성 등과 같은 다양한 생리활성을 갖는 신규 유산균 및 이의 용도를 제공한다. 본 발명에 따른 신규 유산균은 퇴행성 뇌질환 또는 인지기능 장애의 예방, 개선 또는 치료를 위한 기능성 식의약 소재로 사용될 수 있다.
