The disclosure provides methods of treating restless legs syndrome and/or leg cramps comprising administering an effective amount of a monoacetyldiacylglycerol derivative, for example 1-palmitoyl-2-linoleoyl-3-acetylglycerol, together with compositions for use in such methods.本揭露係提供用於治療不寧腿症候群及/或腿痙攣的方法,包括投予有效量的單乙醯二醯甘油衍生物,例如1-棕櫚醯基-2-亞油醯基-3-乙醯甘油,以及用於此方法之組成物。