A safety attachment for application to orthodontic wire in the mouth of a patient comprises a safe-end portion to be crimped onto the orthodontic wire, which once in place on the wire has no sharp edges. The safety attachment comprises upper and lower portions secured to each other by a hinge. One or both of the inner surfaces of the attachment may be textured to improve grip on the wire. The safety attachment may include means for retention by application pliers. Pliers designed for application of a safety attachment have upper and lower beaks, wherein the upper beak includes means to crimp the safe-end portion onto an orthodontic wire and the lower beak includes means to retain the safety attachment prior to applying the safe-end portion to the wire and after application release the safe-end portion leaving it in place on the wire in the patients mouth.