James Donegan;Baoying Liu;Robert Nussenblatt;Lai Wei;Elazar Rabbani;Enzo Biochem, Inc.
发明人:
Nussenblatt, Richard,Liu, Baoying,Wei, Lai,Rabbani, Elazar,Donegan, James J.
申请号：
AU2014256884
公开号：
AU2014256884B2
申请日:
2014.04.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age- related macular degeneration and uveitis. The disclosure also relates to methods of monitoring, diagnosing and/or prognosticating an autoimmune disease in a patient.
