Torsten STEINMETZER,Andrea Schweinitz,Joerg Stuerzebecher,Peter Steinmetzer,Anett Soeffing,Andreas Van De Locht,Silke Nicklisch,Claudia Reichelt,Friedrich-Alexander Ludwig,Alexander Schulze,Mohammed D
申请号：
US13471007
公开号：
US20120225913A1
申请日:
2012.05.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrein, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive.
