PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing loxoprofen or a salt thereof and codeine or the like, which has excellent storage stability.SOLUTION: The pharmaceutical composition contains at least one component selected from the group consisting of codeines, carbinoxamine or a salt thereof, clemastine or a salt thereof, chlorpheniramine or a salt thereof, diphenylpyraline or a salt thereof, bromhexine or a salt thereof, ambroxol or a salt thereof, lysozyme or a salt thereof and dextromethorphan or a salt thereof, and the loxoprofen or the salt thereof in such a manner that the at least one component and the loxoprofen or the salt thereof are substantially not in contact with each other.
