Timothy J. Deming,Jessica R. Kramer,April R. Rodriguez
申请号：
US14770417
公开号：
US09718921B2
申请日:
2014.02.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically modified by oxidation and alkylation of the thioether containing residues. These materials generate self-assembled micelles, vesicles and hydrogels, or emulsions with oil phases. These assemblies can be used to encapsulate and delivery therapeutic molecules. The assemblies can be taken up by cells to release molecules from the assemblies.
