METHODS OF CONTROLLING GENE EXPRESSION AND GENE SILENCING

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专利权人:

SYNGENTA PARTICIPATIONS AG;NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FR;LEVIN, JOSHUA, ZVI;PHILLIPS, KENNETH, LYON;BUDZISZEWSKI, GREGORY, JOSEPH;MEINS, FREDERICK, JR.;GLAZOV, EVGUENI, ALEXANDROVICH

发明人:

LEVIN, JOSHUA, ZVI,PHILLIPS, KENNETH, LYON,BUDZISZEWSKI, GREGORY, JOSEPH,MEINS, FREDERICK, JR.,GLAZOV, EVGUENI, ALEXANDROVICH

申请号：

WO2001EP08825

公开号：

WO0210362(A9)

申请日:

2001.07.30

申请国别(地区):

世界知识产权组织国际局

年份:

2002

代理人:

摘要：

The present invention relates to methods to regulate gene expression in plants. In particular, manipulation of the expression in a plant cell of a nucleotide sequence encoding a polypeptide comprising a 3'-5' exonuclease domain is disclosed. More stable and predictable expression is thus obtained. The present invention also relates to method of increasing or decreasing port-transcriptional silencing. The invention further relates to novel nucleic acid molecules comprising nucleotide sequences encoding polypeptides comprising a 3'-5' exonuclease domain.

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