DNA VACCINE AGAINST MULTITYPES OF AVIAN INFLUENZA VIRUSES AND INFLUENZA VIRUS-LIKE PARTICLES COMPRISING ADJUVANT-FUSED M2 PROTEIN

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专利权人:

Suh-Chin Wu

发明人:

Suh-Chin Wu,Shih-Chang Lin

申请号：

US13449654

公开号：

US20130280296A1

申请日:

2012.04.18

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A DNA vaccine comprising hyperglycosylated mutant HA gene, which is derived from avian influenza virus, is provided. A DNA vaccine composition comprising: (a) the DNA vaccine and (b) a booster is also provided. An influenza virus-like particle comprising adjuvant-fused M2 protein is further provided. A method for eliciting an immune response against a plurality of avian influenza virus subtypes in a subject, comprising delivering the DNA vaccine or the DNA vaccine composition to tissue of the subject is also provided

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