pharmaceutical composition, sealed container, metered dose inhaler, and methods for treating a patient suffering or likely to suffer from a respiratory disorder, to improve the stability of a pharmaceutical composition, to improve aerosolization performance upon storage of a composition and to reduce the global warming potential of a pharmaceutical composition.
It is a pharmaceutical composition. the composition comprises: (i) a drug component comprising at least one tiotropium compound selected from tiotropium and the pharmaceutically acceptable derivatives thereof; and (ii) a propellant component comprising 1,1-difluoroethane (hfa-152a).trata-se de uma composição farmacêutica. a composição compreende: (i) um componente de fármaco que compreende pelo menos um composto de tiotrópio selecionado a partir de tiotrópio e dos derivados farmaceuticamente aceitáveis do mesmo; e (ii) um componente propulsor que compreende 1,1-difluoroetano (hfa-152a).