Bastiaan Nuijen,Ernie Pfadenhauer,Jos H. Beijnen,Luigi Lenaz,Shanta Chawla,Mario Beer
申请号:
US14173734
公开号:
US20140288143A1
申请日:
2014.02.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Therapeutic compositions comprising an indoloquinone compound and various bladder cancer treatments and methods are disclosed. More specifically, bladder cancer treatments include the intravesical administration of apaziquone immediately following transurethral resection. Also disclosed are therapeutic compositions comprising an indoloquinone compound and a formulation vehicle. The formulation vehicle improves the solubility and stability of the indoloquinone compound. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.