Wolfram Eichner;Michele Orlando;Norbert Zander;Frank Hacket;Harald S. Conradt;Klaus Langer;Ronald Frank
发明人:
Wolfram Eichner,Michele Orlando,Norbert Zander,Harald S. Conradt,Frank Hacket,Klaus Langer,Ronald Frank
申请号：
US11518352
公开号：
US08287850B2
申请日:
2006.09.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Conjugates of hydroxyalkyl starch and a protein are provided. The conjugates are formed by a reductive amination reaction between at least one aldehyde group or keto group or hemiacetal group of the hydroxyalkyl starch or of a derivative of the hydroxyalkyl starch, and at least one amino group of the protein, so that the hydroxyalkyl starch or the derivative thereof is covalently linked to the protein via an azomethine linkage or a amino linkage. Methods of producing these conjugates and specific uses of the conjugates also are provided.
