The inventive subject matter is generally directed to an illumination system for staged illumination in an endoscopic procedure. The inventive system generally includes an illumination apparatus supporting a light source that is configured for removable assembly with an endoscope. The assembly is configured for insertion into a natural or artificial passageway in a body. The illumination apparatus has one or more light sources providing a first, relatively high level of illumination suitable for imaging a first, relatively large target area, either alone or in combination with a light source for the endoscope, and after removal of the illumination apparatus from the assembly, the endoscope provides a second relatively lower level of illumination suitable for imaging a relatively small target area.