The endoscope preprocessor of the present invention includes a chemical storage unit that stores a chemical liquid, the first end portion is opened in less than a predetermined water level in the drug solution reservoir, the predetermined second end of the chemical storage outsiders A sampling tube opened at a position higher than the water level, a first chamber in which the second end portion of the sampling tube is open, a communication port communicating with the opening and the first chamber is formed and a second chamber, connecting said first chamber and said communication port, and a constriction portion having a narrower inside diameter than the inner diameter of the first chamber, in the first chamber, the first position for closing the constriction, and A first advancing and retreating portion that advances and retracts between a first position in which the stenosis portion is separated from the stenosis portion and a second position in which the stenosis portion is opened more than the stenosis portion, and a second advancement portion that is disposed in the constriction portion or the first advancement / And a retention portion that keeps the one advance / retreat portion at the first position.本発明の内視鏡リプロセッサは、薬液を貯留する薬液貯留部と、第1端部が前記薬液貯留部内の所定水位以下で開口し、第2端部が前記薬液貯留部外のうち前記所定水位よりも高い位置で開口している採取管と、前記採取管の前記第2端部が内部で開口している第1室と、開口部および前記第1室に連通する連通口が形成された第2室と、前記第1室および前記連通口をつなぎ、前記第1室の内径よりも狭い内径を有する狭窄部と、前記第1室内において、前記狭窄部を閉塞する第1位置、および前記第1位置よりも前記狭窄部から離れて前記狭窄部を開放する第2位置、の間で進退移動する第1進退部と、前記狭窄部、または前記第1進退部に配置され、前記第1進退部を前記第1位置に留める滞留部と、を含む。