INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA
发明人:
Song LI,Wu ZHONG,Shuang CAO,Lili WANG,Zhibing ZHENG,Junhai XIAO,Xinbo ZHOU
申请号:
US14902986
公开号:
US20160137619A1
申请日:
2014.07.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development.