Bei einem medizinischen Instrument zum Schneiden von biologischem, insbesondere menschlichem Gewebe mittels einem Schneidmodul (5) mit einer Schneide (21), welches in ein Handmodul (1) eingesetzt ist, soll das Schneidmodul (5) in dem Handmodul (1) lösbar festgelegt sein.The instrument (R) has a cutting module (5) detachably frontwardly fixed into a hand module (1), and a valve module inserted into the hand module. The cutting module and/or the valve module are disposable while the hand module is reusable. The hand module is connected with an external motor by a flexible shaft. The cutting module comprises a circumferential carrier and a hollow cutting pipe, which is rotated around a rotation axle. The carrier is formed as a plastic part, and slide bearing rings are pressed on the cutting module and/or on the carrier in a force-fit manner.