1. A method for simulating the spread of a contrast medium, including a contrast enhancement agent, administered to a patient using a physiologically sound pharmacokinetic model, comprising: including at least one of the non-linear saturation periods in the peripheral venous compartment in a physiologically sound pharmacokinetic model, or at least , one configurable transport delay through at least one compartment. 2. The method according to claim 1, wherein a physiologically based pharmacokinetic model is adapted to estimate the gain time curve for the patient’s area of interest. The method of claim 1, wherein the at least one configurable transport delay is configurable at least partially based on at least one variable of a particular patient. The method according to claim 1, wherein the physiologically based pharmacokinetic model is adapted to simulate the spread of the contrast medium after the injection of the contrast medium is stopped. The method according to claim 4, wherein a physiologically based pharmacokinetic model models the volumetric rate of blood flow and its effect on the distribution of contrast medium. The method according to claim 5, wherein a physiologically based pharmacokinetic model models the effect on the distribution of contrast medium upon injection of a liquid not containing a contrast enhancement agent after injection of the contrast medium. The method according to claim 1, where at least one parameter for a physiologically based pharmacokinetic model is determined at least partially based on data from1. Способ моделирования распространения контрастного вещества, включая средство усиления контрастности, введенное пациенту с использованием физиологически обоснованной фармакокинетической модели, содержащий: включение в физиологически обоснованную фармакокинетическую модель, по меньшей мере, одного из нелинейных периодов насыщения в периферическом венозном компартменте, или, по меньшей мере, одну конфигурируемую транспортную задержку чере
