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INHIBITION OF HISTONE ACETYLTRANSFERASES BY CTK7A AND METHODS THEREOF
专利权人:
Tapas Kumar Kundu
发明人:
Tapas Kumar Kundu,Mohammed Arif,Kempegowra Mantelingu,Gopinath Kadaganur Srinivasachar
申请号:
US13394541
公开号:
US20120165384A1
申请日:
2010.09.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present disclosure relates to a method for inhibiting histone acetyltransferases by derivative of curcumin, particularly CTK7A. The present disclosure also relates to identification of induction of autoacetylation of p300 and its inhibition by CTK7A. The disclosure also relates to induction of NPM1 and GAPDH overexpression and corresponding hyperacetylation of histone and methods thereof.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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