David M. Burns;Yun-Long Li;Brian Metcalf;Colin Zhang;Ding-Quan Qian;Jincong Zhuo;Meizhong Xu;Chunhong He;Wenqing Yao
发明人:
Jincong Zhuo,Meizhong Xu,Chunhong He,Colin Zhang,Ding-Quan Qian,David M. Burns,Yun-Long Li,Brian Metcalf,Wenqing Yao
申请号:
US12813148
公开号:
US08461330B2
申请日:
2010.06.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.