The device (4) for removing air from blood in a extracorporeal circuit (100) comprises: a venous filter (6, 20) having a venous inlet (310) and a venous outlet (37; 37'); an arterial filter (5, 21) having an arterial inlet (30) and an arterial outlet (410); said venous filter (6, 20) and said arterial filter (5, 21 ) being accommodated in a first housing chamber (106) and a second housing chamber (105) respectively, both being defined in a common housing body (104; 504) in which said venous inlet (310) and venous outlet (37; 37') and said arterial inlet (30) and arterial outlet (410) are formed.