Kyungpook National University Industry-Academic Cooperation Foundation
发明人:
Choi, Myung-Sook,Kwon, Eun-Young,Kim, Ye Jin,Ryu, Ri
申请号:
AU2017204817
公开号:
AU2017204817B1
申请日:
2017.07.12
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2017204817B120181108.pdf#####ABSTRACT Provided are a composition for preventing, improving or treating obesity, which comprises a Platycodon grandiflorum extract as an active ingredient and a method for preparing an Platycodon grandiflorum extract with an improved anti5 obesity effect. The Platycodon grandiflorum extract shows an effect of inhibiting increases in body weight and fat mass caused by a high-fat diet for normalization, an increase in fasting blood glucose and a decrease in energy expenditure in a dietinduced obesity mouse model. In addition, compared to a Platycodon grandiflorum extract prepared by a conventional extraction method, the Platycodon grandiflorum 10 extract shows a more excellent effect of inhibiting increases in body weight and fat mass, fasting blood glucose, and blood lipid and adipokine contents in experiments, resulting in an excellent anti-obesity effect. Therefore, the Platycodon grandiflorum extract prepared by the present method is expected to be useful for preventing obesity and treating obesity-related complications that can be caused by an increase 15 in fat mass as well as obesity.