TAHRI, ABDELLAH,JONCKERS, TIM HUGO MARIA,RABOISSON, PIERRE JEAN-MARIE BERNARD,VENDEVILLE, SANDRINE MARIE HELENE,COOYMANS, LUDWIG PAUL,DEMIN, SAMUEL DOMINIQUE
申请号：
CA2873921
公开号：
CA2873921A1
申请日:
2013.06.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention is concerned with novel 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with benzimidazoles having formula (I) stereoisomeric forms thereof, and the pharmaceutically acceptable addition salts, and the solvates thereof, wherein R4, R5, Z and Het have the meaning defined in the claims. The compounds according to the present invention are useful as inhibitors on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
