A multi-component microbiocidal contraceptive intravaginal ring-shaped metal mesh device comprising a ring-shaped metal mesh structure comprising a ring matrix that surrounds a fibrous metal mesh attached thereto and held within the inside diameter of the ring and a polymeric coating covering the ring-shaped metal mesh structure, where each of the ring matrix and the polymeric coating comprise at least one polymeric drug release substrate for controlled independent release of at least one contraceptive agent and at least one bioactive agent, and where at least one bioactive agent is selected from the group consisting of metronidazole, miconazole, ketoconazole, fluconazole, tobramycin, rapamycin, amphotericin, 5-fluorocytosine, ciprofloxacin, tetracycline, doxycycline, zidovudine, acyclovir, penciclovir, ganciclovir, cidofovir, lamivudine, zalcitabine, valacicl OVIR, stavudine, ritonavir, indinavir, didanosine, didesoxiadinosina, paclitaxel, mitomycin, 5-fluorouracil, leflunomide, enfuvirtide, clotrimazole, terbinafine, chlorhexidine, mafenide, clindamycin, gemcitabine, erythromycin, ofloxacin, ceftriaxone and cefpodoxime, wherein the matrix comprises ring silicone and where the fibrous metal mesh comprises polyester, and where the ring matrix comprises at least one contraceptive agent and where the polymeric coating contains at least one of said bioactive agents.Un dispositivo de malla metálica con forma de anillo intravaginal anticonceptivo microbiocida de multi-componente que comprende una estructura de malla metálica con forma de anillo que comprende una matriz de anillo que rodea una malla metálica fibrosa unida a la misma y mantenida en el diámetro interior del anillo y un revestimiento polimérico que cubre la estructura de malla metálica con forma de anillo, donde cada uno de la matriz de anillo y el revestimiento polimérico comprenden al menos un sustrato polimérico de liberación de fármaco para la liberación controlada independiente de al menos un agente ant
